rEVO Biologics, Inc.'s technology and products have been well reported in scientific literature and at scientific meetings. A selected bibliography is below.
Selected Publications on Antithrombin and ATryn® Antithrombin (Recombinant)
Evans S, Malia S, et al. (2016). The compatibility of ATryn (antithrombin [recombinant]) when coadministered in an intravenous line along with commonly used medications. World Journal Of Pharmacy and Pharmaceutical Sciences:5,234-45.
Paidas MJ, Forsyth C, Quere I, et al. (2014). Perioperative and peripartum prevention of venous thromboembolism in patients with hereditary antithrombin deficiency using recombinant antithrombin therapy. Blood Coagulation and Fibrinolysis:00;1-7.
DeJongh J, Frieling J, Lowry S, Dreth H-J (2014). Pharmacokinetics of recombinant human antithrombin in delivery and surgery patients with hereditary antithrombin deficiency. Clin Appl Thromb Hemost 20:355-64.
Baumann Kreuziger LM, Prosen TL, Reding MT (2013). Use of recombinant human antithrombin concentrate in pregnancy. International Journal of Women's Health 5;583-6.
Patnaik MM and Moll S (2008). Inherited antithrombin deficiency: a review. Haemophilia 14:1220-1239.
Konkle B, Bauer K, Weinstein R, Greist A, Holmes H, Bonfiglio J. (2003). Use of recombinant human antithrombin (AT) in patients with congenital AT deficiency undergoing surgical procedures. Transfusion 43: 390-4.
Edmunds T, Van Patten SM, Pollock J, Hanson E, Bernasconi R, Higgins E, Manavalan P, Ziomek C, Meade H, McPherson JM, Cole ES. (1998). Transgenically produced human antithrombin: structural and functional comparison to human plasma-derived antithrombin. Blood Jun 15; 91(12): 4561-71.
Echelard Y, Meade H, Ziomek C (2005). The First Biopharmaceutical from Transgenic Animals: ATryn®. Modern Biopharmaceuticals. WILEY-VCH Verlag GmbH & Co. KGaA; Kap. 4-11: 995-1016.
Maclean PS and Tait RC (2007). Hereditary and acquired antithrombin deficiency, epidemiology, pathogenesis and treatment options. Drugs. 67(10):1429-40.
Buchanan GS, Rodgers GM, Branch W (2003). The inherited thrombophilias: genetics, epidemiology, and laboratory evaluation. Best Pract Res Clin Obstet Gynaecol. 17(3): 397-411.
Walker ID, Greaves M, Preston FE (2001). Investigation and management of heritable thrombophilia. Br J Haematol. 114: 512-28.